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Glutathione for Chronic Fatigue: What to Expect

Oct 13, 2025
Glutathione for Chronic Fatigue: What to Expect
Chronic fatigue syndrome (CFS) isn’t just about feeling tired — it’s about continually low levels of energy that interfere with virtually every aspect of your life. Here, learn how glutathione IV infusions can play a role in managing CFS symptoms.

Most people feel tired and worn out from time to time, but for people with chronic fatigue syndrome (CFS), those feelings of fatigue don’t go away after a good night’s rest. Instead, they persist, making even simple, day-to-day routines extremely difficult and frustrating. What’s more, they may come with other issues, like difficulty concentrating or flu-like symptoms.

While the cause of CFS isn’t known, researchers suspect the condition could be related to low levels of glutathione, an antioxidant that helps cells access and use energy. It makes sense, then, that low levels of glutathione can lead to low energy levels and persistent feelings of fatigue.

At Advanced Medical Care, our caring providers help patients manage CFS symptoms with wellness therapies — including glutathione IV infusions. These treatments deliver glutathione and other important micronutrients directly into the bloodstream, providing cells with the energy necessary for optimal function. Here’s what you should know about this IV therapy.

Chronic fatigue and cellular energy

Also called myalgic encephalomyelitis, chronic fatigue syndrome is a highly complex illness that affects multiple systems in your body, including your metabolic processes, the system your body uses to convert food to energy that can be used by your cells. 

Cells contain special structures called mitochondria, routinely referred to as the powerhouses of the cell. That’s because mitochondria play key roles in converting nutrients and oxygen into a form of usable energy called ATP, which stands for adenosine triphosphate. 

Research shows that people with CFS often have mitochondrial dysfunction, impairing the mitochondria’s ability to provide cells with energy. That means even with enough rest or fuel, your body is simply unable to produce the energy it needs to maintain its normal functions, leaving you feeling drained, tired, and lethargic.

Glutathione plays an essential role in maintaining mitochondrial health and function. Interestingly, CFS is also associated with low levels of this important antioxidant. That link is why glutathione has become a talked-about target for CFS researchers in recent years.

Glutathione infusion therapy for fatigue symptoms

Antioxidants like glutathione also help fight off oxidative stress and inflammation, issues that can increase the risk of mitochondrial dysfunction. Here’s what to expect with glutathione IV treatment.

This infusion therapy delivers glutathione intravenously, bypassing your digestive system where antioxidants can be broken down and diluted. Direct delivery into your bloodstream also avoids problems with absorption that can occur in your stomach or intestines; it helps ensure that your cells receive more glutathione for enhanced benefits.

Glutathione provides ramped-up support for mitochondria, helping them convert nutrients into energy more efficiently and effectively. At the same time, glutathione helps neutralize free radicals and reduce inflammation for long-term health benefits.

Like many medical therapies, glutathione IV infusion works best when combined with good personal habits, like a healthy diet, regular exercise, stress management activities, and regular sleep routines. Infusion therapy is entirely customizable, so your body can receive the support it needs even as those needs change.

Learn more about glutathione therapy

If you’re battling chronic fatigue, glutathione therapy could offer the solution you’ve been looking for. While this treatment isn’t a cure for CFS, glutathione could help relieve symptoms and restore a better, more balanced quality of life.

To learn more about glutathione IV infusions, request an appointment online or over the phone with the team at Advanced Medical Care in Forest Hills, Queens, and Brighton Beach, Brooklyn, New York.

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At Advanced Medical Care, care is not just a part of our name — it is in our hearts. Our providers strive to put our patients first and find solutions to meet their needs on every level. If you’re ready to start improving your health, we encourage you to schedule an appointment at our office in Queens or Brooklyn.